Description

6-(2-Trifluoromethoxyphenyl)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted biphenyl structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the stability of the trifluoromethoxy group.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalytic and material science applications.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Intermediate for producing complex, fluorinated organic compounds with specific electronic properties.

Basic Information

Product Name	6-(2-Trifluoromethoxyphenyl)-Nicotinic Acid
CAS No.	197847-94-2
Molecular Formula	C13H8F3NO3
Molecular Weight	283.21 g/mol
Synonyms	2-(Trifluoromethoxy)-[3,3'-bipyridine]-5-carboxylic Acid; 6-[2-(Trifluoromethoxy)phenyl]pyridine-3-carboxylic Acid; 5-Carboxy-2'-(trifluoromethoxy)-[3,3'-bipyridine]; Nicotinic acid, 6-[2-(trifluoromethoxy)phenyl]-; 197847-94-2; 6-(2-Trifluoromethoxy-phenyl)-nicotinic acid
EINECS	Contact for details

Quality Control

Our 6-(2-Trifluoromethoxyphenyl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.