Description

5-Pyridin-4-Yl-4H-Pyrazole-3-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its core value lies in its versatile pyrazole-pyridine scaffold, which is crucial for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Acts as a chelating agent or ligand precursor in coordination chemistry and catalyst design for organic transformations.
• Material Science: Investigated as a monomer or functional additive for creating specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Pyridin-4-Yl-4H-Pyrazole-3-Carboxylic Acid
CAS No.	197775-45-4
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	4-(1H-Pyrazol-5-yl)pyridine-3-carboxylic Acid; 5-(4-Pyridinyl)-1H-pyrazole-3-carboxylic Acid; 5-(Pyridin-4-yl)-1H-pyrazole-3-carboxylic Acid; 5-(4-Pyridyl)pyrazole-3-carboxylic Acid; 3-Pyrazolecarboxylic acid, 5-(4-pyridinyl)-; 1H-Pyrazole-3-carboxylic acid, 5-(4-pyridinyl)-; 4-(3-Carboxy-1H-pyrazol-5-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Pyridin-4-Yl-4H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is a strong acid/organic solvent and should be handled with appropriate personal protective equipment. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.