Description

tert-Butyl 4-[Acetyl(Methyl)Amino]Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and chemical manufacturers engaged in the synthesis of complex molecules for medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization for introducing specific functional groups.
• API Synthesis: Integral in the production route for active pharmaceutical ingredients that require a functionalized piperidine scaffold.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Research & Development: Employed in academic and industrial R&D labs for developing new synthetic methodologies and novel compounds.

Basic Information

Product Name	tert-Butyl 4-[Acetyl(Methyl)Amino]Piperidine-1-Carboxylate
CAS No.	197727-57-4
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	1-Boc-4-(N-methylacetamido)piperidine; 1-(tert-Butoxycarbonyl)-4-[(methylamino)acetyl]piperidine; 4-(Acetyl(methyl)amino)-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl 4-(N-methylacetamido)piperidine-1-carboxylate; 4-(N-Methylacetamido)piperidine-1-carboxylic acid tert-butyl ester; N-Methyl-N-(1-Boc-4-piperidyl)acetamide; 197727-57-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[Acetyl(Methyl)Amino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability for our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.