Description

1-o-Acetyl-2-Deoxy-3,5-Di-o-Benzoyl-2-Fluoro-4-Thio-D Arabinofuranone is a high-value, fluorinated carbohydrate derivative, specifically a thio-sugar nucleoside precursor. This compound matters as a critical synthetic intermediate in the development of novel antiviral and anticancer therapeutics, where its unique fluorine and sulfur modifications are leveraged for enhanced biological activity and metabolic stability. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions focused on nucleoside chemistry and medicinal chemistry programs targeting viral and oncological diseases.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated nucleoside analogs and prodrugs.
• Antiviral Drug Research: Used in the development of novel antiviral agents targeting viruses such as hepatitis, influenza, and herpes.
• Anticancer Agent Development: Serves as a precursor for potential chemotherapeutic compounds that interfere with DNA/RNA synthesis.
• Medicinal Chemistry & SAR Studies: Enables structure-activity relationship studies by introducing fluorine and sulfur moieties into sugar scaffolds.
• Biochemical Probe Synthesis: Utilized to create labeled or modified nucleosides for studying enzymatic mechanisms and biological pathways.
• Academic & Industrial R&D: A valuable reagent for advanced organic synthesis and methodology development in carbohydrate chemistry.

Basic Information

Product Name	1-o-Acetyl-2-Deoxy-3,5-Di-o-Benzoyl-2-Fluoro-4-Thio-D Arabinofuranone
CAS No.	197647-16-8
Molecular Formula	C22H19FO6S
Molecular Weight	430.45 g/mol
Synonyms	1-O-Acetyl-2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-α/β-D-arabinofuranose; 2-Fluoro-4-thioarabinofuranosyl Derivative; 4-Thio-2-fluoroarabinofuranose Acetyl Benzoyl Ester; 1-Acetyl-2-fluoro-3,5-dibenzoyl-4-thio-D-arabinofuranose; Fluorinated 4-Thiosugar Nucleoside Precursor; CAS 197647-16-8; 2-Deoxy-2-fluoro-4-thio-D-arabinofuranose 1-acetate 3,5-dibenzoate
EINECS	Contact for details

Quality Control

Our 1-o-Acetyl-2-Deoxy-3,5-Di-o-Benzoyl-2-Fluoro-4-Thio-D Arabinofuranone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.