Description

(2R,3R)-3-(3,4-Bis-Benzyloxy-Phenyl)-2,3-Dihydroxy-Propionic Acid Methyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical building block for the development of complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex, stereospecific drugs.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex molecular architectures, leveraging its diol and ester functionalities.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies exploring new asymmetric synthesis methodologies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where precise stereochemical control is required.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	(2R,3R)-3-(3,4-Bis-Benzyloxy-Phenyl)-2,3-Dihydroxy-Propionic Acid Methyl Ester
CAS No.	197244-11-4
Molecular Formula	C24H24O6
Molecular Weight	408.45 g/mol
Synonyms	Methyl (2R,3R)-3-(3,4-bis(benzyloxy)phenyl)-2,3-dihydroxypropanoate; (2R,3R)-Methyl 3-(3,4-dibenzyloxyphenyl)-2,3-dihydroxypropionate; 3,4-Di-O-benzyl-protected Dihydroxy Methyl Ester; (R,R)-Dihydroxy Ester Intermediate; 197244-11-4; Methyl (2R,3R)-2,3-dihydroxy-3-[3,4-bis(phenylmethoxy)phenyl]propanoate
EINECS	Contact for details

Quality Control

Our (2R,3R)-3-(3,4-Bis-Benzyloxy-Phenyl)-2,3-Dihydroxy-Propionic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.