Description

1H-Pyrazole-3-Carboxylic Acid, 1-Methyl-4-(Trifluoromethyl)-, Ethyl Ester is a high-value pyrazole derivative, a versatile and critical building block in advanced organic synthesis. Its core value proposition lies in its trifluoromethyl-substituted pyrazole scaffold, which is instrumental in modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Ligand & Catalyst Precursor: Potential use in the synthesis of specialized ligands for catalysis or metal-organic frameworks (MOFs) due to its nitrogen-rich structure.
• Material Science Applications: Can be utilized as a monomer or functional additive in the development of advanced polymers with specific electronic or surface properties.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 1-Methyl-4-(Trifluoromethyl)-, Ethyl Ester
CAS No.	197226-81-6
Molecular Formula	C8H9F3N2O2
Molecular Weight	222.17 g/mol
Synonyms	Ethyl 1-Methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylate; 1-Methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic Acid Ethyl Ester; 4-(Trifluoromethyl)-1-methyl-1H-pyrazole-3-carboxylic Acid Ethyl Ester; 1-Methyl-4-trifluoromethylpyrazole-3-carboxylic Acid Ethyl Ester; 1-Methyl-4-trifluoromethyl-1H-pyrazole-3-carboxylate Ethyl Ester; Ethyl 1-Methyl-4-trifluoromethylpyrazole-3-carboxylate; 1-Methyl-4-(trifluoromethyl)pyrazole-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carboxylic Acid, 1-Methyl-4-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.