Description

2,6-Bis-(T-Butyl Dimethylsilyloxy) Phenol is a high-purity, organosilicon-protected phenol derivative, serving as a critical synthetic intermediate and protecting group reagent. Its primary value lies in providing steric protection for phenolic hydroxyl groups during complex multi-step organic syntheses, particularly in sensitive environments. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially where selective protection of phenolic OH groups is required.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the phenol moiety needs temporary protection from harsh reaction conditions.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the production of specialty polymers, resins, and silicon-based materials.
• Organic Synthesis Reagent: Employed as a versatile protecting group agent in academic and industrial research laboratories for complex organic transformations.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal-catalyzed reactions due to its sterically hindered structure.

Basic Information

Product Name	2,6-Bis-(T-Butyl Dimethylsilyloxy) Phenol
CAS No.	197014-35-0
Molecular Formula	C20H38O3Si2
Molecular Weight	382.69 g/mol
Synonyms	2,6-Bis(tert-Butyldimethylsilyloxy)phenol; 2,6-Bis[(1,1-dimethylethyl)dimethylsilyl]oxy]phenol; Phenol, 2,6-bis[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 2,6-Di-O-tert-butyldimethylsilyl phenol; 2,6-Bis(TBDMS-oxy)phenol; 2,6-Bis(tert-butyldimethylsiloxy)benzene-1-ol; 2,6-BDTBS-Phenol
EINECS	Contact for details

Quality Control

Our 2,6-Bis-(T-Butyl Dimethylsilyloxy) Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. For long-term storage, consider using desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.