Description

Ethyl 3-(3-Fluoro-4-Methoxyphenyl)-3-Oxopropanoate is a high-purity fluorinated aromatic β-ketoester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic combination of a reactive β-ketoester moiety with a substituted fluoromethoxyphenyl ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where the fluorine atom and methoxy group are key pharmacophores.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing complex drug candidates, especially in therapeutic areas targeting the central nervous system (CNS) and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorinated aromatic structure enhances biological activity and stability.
• Chemical Research & Development: Serves as a versatile precursor for Claisen condensations, Michael additions, and heterocycle formation (e.g., pyrazoles, isoxazoles) in academic and industrial R&D labs.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymers and coordination complexes.
• Fine Chemical Production: Employed in the custom synthesis of fluorinated fine chemicals and specialty additives.

Basic Information

Product Name	Ethyl 3-(3-Fluoro-4-Methoxyphenyl)-3-Oxopropanoate
CAS No.	195708-39-5
Molecular Formula	C12H13FO4
Molecular Weight	240.23 g/mol
Synonyms	Ethyl 3-(3-Fluoro-4-methoxyphenyl)-3-oxopropanoate; 3-(3-Fluoro-4-methoxyphenyl)-3-oxopropanoic Acid Ethyl Ester; Ethyl 3-Oxo-3-(3-fluoro-4-methoxyphenyl)propanoate; Ethyl (3-Fluoro-4-methoxybenzoyl)acetate; 3-Fluoro-4-methoxybenzoylacetic Acid Ethyl Ester; Acetic acid, (3-fluoro-4-methoxybenzoyl)-, ethyl ester; Ethyl β-(3-Fluoro-4-methoxybenzoyl)propionate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Fluoro-4-Methoxyphenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.