Description

2-Methyl-4-Trifluoromethyl-Nicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a methyl and a trifluoromethyl group on the nicotinic acid core, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Methyl-4-Trifluoromethyl-Nicotinic Acid
CAS No.	195447-85-9
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-Methyl-4-(trifluoromethyl)nicotinic acid; 4-(Trifluoromethyl)-2-methylpyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-methyl-4-(trifluoromethyl)-; 2-Methyl-4-trifluoromethylnicotinic acid; 195447-85-9; Nicotinic acid, 2-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Trifluoromethyl-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.