Description

Proline, 5-Methyl-, Methyl Ester (9Ci) is a specialized proline derivative, a key chiral building block in organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require high-purity, structurally defined intermediates for peptide mimetics, active pharmaceutical ingredients (APIs), and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in medicinal chemistry to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for developing advanced, chiral pesticides and herbicides.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in stereoselective chemical transformations.
• Biochemical Research: Utilized in proteomics and enzyme studies as a modified amino acid derivative.
• Fine Chemical Production: A key intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Proline, 5-Methyl-, Methyl Ester (9Ci)
CAS No.	195311-23-0
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	Methyl 5-methylprolinate; 5-Methylproline methyl ester; Methyl (2S,5S)-5-methylpyrrolidine-2-carboxylate; L-Proline, 5-methyl-, methyl ester; (2S,5S)-5-Methylpyrrolidine-2-carboxylic acid methyl ester; Methyl 5-methyl-L-prolinate; 5-Methyl-L-proline methyl ester
EINECS	Contact for details

Quality Control

Our Proline, 5-Methyl-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.