Description

2-Chloro-4-Hydroxy-5-Iodo-Benzoic Acid Methyl Ester is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring chlorine, iodine, and a phenolic hydroxyl group, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the research and production of advanced organic electronic materials, liquid crystals, and polymers.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2-Chloro-4-Hydroxy-5-Iodo-Benzoic Acid Methyl Ester
CAS No.	195250-54-5
Molecular Formula	C8H6ClIO3
Molecular Weight	312.49 g/mol
Synonyms	Methyl 2-Chloro-4-hydroxy-5-iodobenzoate; Benzoic acid, 2-chloro-4-hydroxy-5-iodo-, methyl ester; 2-Chloro-4-hydroxy-5-iodobenzoic acid methyl ester; Methyl 5-iodo-2-chloro-4-hydroxybenzoate; 5-Iodo-2-chloro-4-hydroxybenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Hydroxy-5-Iodo-Benzoic Acid Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the rigorous standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.