Description

2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2S)-(9Ci) is a chiral, non-racemic compound belonging to the class of tetrahydrofuran derivatives, serving as a valuable synthetic intermediate. Its defined stereochemistry and functionalized structure make it a critical building block for the development of complex, optically active molecules. This high-purity intermediate is essential for research and production in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug research.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereocenters.
• Fine Chemical Production: Building block for creating complex agrochemicals, flavors, and fragrances requiring specific enantiomeric purity.
• Academic & Industrial R&D: Serves as a reference standard and reagent in methodological development for organic and medicinal chemistry.
• Ligand and Catalyst Development: Potential precursor for novel chiral ligands used in transition metal catalysis.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2S)-(9Ci)
CAS No.	195067-06-2
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(2S)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; Methyl (2S)-tetrahydro-5-methoxy-2-furoate; (S)-5-Methoxytetrahydrofuran-2-carboxylic acid methyl ester; (2S)-5-Methoxy-2-tetrahydrofurancarboxylic acid methyl ester; (S)-Methyl 5-methoxytetrahydrofuran-2-carboxylate; Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester, (2S)-; 195067-06-2; (2S)-rel-5-Methoxytetrahydro-2-furancarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through advanced analytical techniques including Chiral HPLC, GC, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.