Description

Benzenepropanoic Acid, -α--[(Acetyloxy)Methyl]-, (-α-R)- (9Ci) is a chiral, non-racemic organic compound featuring a benzenepropanoic acid core with an acetyloxymethyl substituent at the alpha position. This specific stereochemistry and functional group arrangement make it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block for organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators where its specific stereochemistry is crucial for bioactivity.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing complex molecules, flavors, fragrances, and specialty polymers in research and pilot-scale production.
• Asymmetric Catalysis Studies: Employed as a standard or substrate in academic and industrial research to develop and test new chiral catalysts and synthetic methodologies.
• Bioconjugate Chemistry: Potential use in creating prodrugs or antibody-drug conjugates (ADCs) due to its functionalizable acid and ester groups.

Basic Information

Item	Detail
Product Name	Benzenepropanoic Acid, -α--[(Acetyloxy)Methyl]-, (-α-R)- (9Ci)
CAS No.	195056-66-7
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(R)-α-[(Acetyloxy)methyl]benzenepropanoic acid; (R)-2-(Acetoxymethyl)-3-phenylpropanoic acid; (αR)-α-[(Acetyloxy)methyl]benzenepropanoic acid; (R)-3-Phenyl-2-(acetoxymethyl)propionic acid; Phenylpropanoic acid, α-[(acetyloxy)methyl]-, (αR)-; 195056-66-7; (R)-Acetoxymethyl phenylpropionic acid
EINECS	Contact for details

Quality Control

Our production of Benzenepropanoic Acid, -α--[(Acetyloxy)Methyl]-, (-α-R)- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.