Description

Methyl 3-[tert-Butoxycarbonyl-(2-Methoxy-2-Oxo-Ethyl)Amino]Propanoate CAS NO 194924-94-2 is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex, biologically active molecules. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide synthesis and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly for introducing specific amino acid-like motifs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected aspartic acid or glutamic acid derivative.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Protease Inhibitor Development: Integral in creating molecules that mimic peptide substrates for enzyme inhibition studies.
• Bioconjugation & Linker Chemistry: Employed in the design of chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science: Used in the synthesis of specialized polymers and dendrimers with tailored functional groups.

Basic Information

Product Name	Methyl 3-[tert-Butoxycarbonyl-(2-Methoxy-2-Oxo-Ethyl)Amino]Propanoate
CAS No.	194924-94-2
Molecular Formula	C13H23NO7
Molecular Weight	305.32 g/mol
Synonyms	Boc-Asp(OMe)-OMe; tert-Butyl (2S)-2-[(methoxycarbonyl)methyl]-4-methoxy-4-oxobutylcarbamate; Methyl N-(tert-Butoxycarbonyl)-L-aspartate β-methyl ester; Methyl (2S)-2-[(tert-Butoxycarbonyl)amino]-4-methoxy-4-oxobutanoate; Boc-L-Asp(OMe)-OMe; N-Boc-L-Aspartic acid β-methyl ester; (S)-Methyl 2-((tert-butoxycarbonyl)amino)-4-methoxy-4-oxobutanoate; Methyl 3-[(tert-butoxycarbonyl)(2-methoxy-2-oxoethyl)amino]propanoate
EINECS	Contact for details

Quality Control

Our Methyl 3-[tert-Butoxycarbonyl-(2-Methoxy-2-Oxo-Ethyl)Amino]Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and chiral analysis, to meet the exacting standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.