Description

8-Oxa-2-Aza-Spiro[4.5]Decan-3-One is a high-value, heterocyclic organic compound featuring a unique spirocyclic structure that serves as a critical synthetic intermediate. This compound matters because it provides a versatile and sophisticated scaffold for constructing complex molecules in advanced pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with new modes of action.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science: A precursor for advanced polymers and ligands used in catalysis and material design.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and contract research organizations (CROs).
• Custom Synthesis: The foundation for bespoke chemical synthesis services for clients requiring specific, complex molecular architectures.

Basic Information

Product Name	8-Oxa-2-Aza-Spiro[4.5]Decan-3-One
CAS No.	194862-84-5
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Oxa-2-azaspiro[4.5]decan-3-one; 2-Aza-8-oxaspiro[4.5]decan-3-one; 3-Oxo-8-oxa-2-azaspiro[4.5]decane; 1-Oxa-4-azaspiro[4.5]decan-3-one (tautomeric form); OAD; Spirocyclic lactam; Tetrahydro-2H-1,3-oxazin-2-one, hexahydrospiro-; Hexahydrospiro[cyclopentane-1,2'-[1,3]oxazinan]-3'-one
EINECS	Contact for details

Quality Control

Our 8-Oxa-2-Aza-Spiro[4.5]Decan-3-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.