Description

2-Iodomethylbenzoic Acid Ethyl Ester is a versatile and high-value iodinated aromatic building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily used by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce functionalized benzyl groups into target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a functionalized benzyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in various palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Iodomethylbenzoic Acid Ethyl Ester
CAS No.	194491-03-7
Molecular Formula	C10H11IO2
Molecular Weight	290.10 g/mol
Synonyms	Ethyl 2-(Iodomethyl)benzoate; Benzoic acid, 2-(iodomethyl)-, ethyl ester; 2-(Iodomethyl)benzoic Acid Ethyl Ester; o-Iodomethylbenzoic Acid Ethyl Ester; Ethyl o-Iodomethylbenzoate; (2-(Iodomethyl)phenyl)methanol, ethyl ester (tautomeric form); CAS 194491-03-7
EINECS	Contact for details

Quality Control

Our 2-Iodomethylbenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.