Description

5-tert-Butyl-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-purity, versatile indole derivative serving as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique sterically hindered structure makes it invaluable for constructing complex molecules with specific biological activity. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new generation pesticides and herbicides due to its bioactive indole core.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photostabilizers in advanced polymer systems.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and enzyme inhibitors.
• Ligand Synthesis: Used to create specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-tert-Butyl-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	194490-18-1
Molecular Formula	C₁₅H₁₉NO₂
Molecular Weight	245.32 g/mol
Synonyms	Ethyl 5-tert-butyl-1H-indole-2-carboxylate; 5-(1,1-Dimethylethyl)-1H-indole-2-carboxylic acid ethyl ester; 5-tert-Butylindole-2-carboxylic acid ethyl ester; 194490-18-1; Ethyl 5-(tert-butyl)indole-2-carboxylate; 2-Carbethoxy-5-tert-butylindole; 5-tert-Butyl-1H-indole-2-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-tert-Butyl-1H-Indole-2-Carboxylic Acid Ethyl Ester adheres to stringent cGMP and ISO 9001 quality management principles. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide full traceability and detailed Certificates of Analysis (COA) to ensure compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.