Description

2H-Cyclopenta[B]Furan-2-One, 3,3A,4,6A-Tetrahydro-3-(Hydroxymethylene)-, [3As-(3Z,3Aalpha,6Aalpha)]- (9Ci) CAS NO 194468-85-4 is a specialized, high-purity chemical intermediate characterized by its unique fused cyclopenta-furanone structure with a hydroxymethylene functional group. This compound matters as a versatile chiral building block for synthesizing complex molecules, offering precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

This advanced intermediate serves as a key precursor in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: For the research and development of novel drug candidates, particularly in areas requiring complex, chiral molecular architectures.
• Agrochemical Synthesis: As a building block for creating new, high-performance active ingredients for crop protection products.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, flavors, and fragrances where specific stereochemistry is critical.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Material Science Precursor: Potential use in the development of advanced organic materials and polymers with specific functional properties.

Basic Information

Product Name	2H-Cyclopenta[B]Furan-2-One, 3,3A,4,6A-Tetrahydro-3-(Hydroxymethylene)-, [3As-(3Z,3Aalpha,6Aalpha)]- (9Ci)
CAS No.	194468-85-4
Molecular Formula	C8H8O3
Molecular Weight	152.15 g/mol
Synonyms	(3Z,3aα,6aα)-3,3a,4,6a-Tetrahydro-3-(hydroxymethylene)-2H-cyclopenta[b]furan-2-one; 3-(Hydroxymethylene)-3a,4,6,6a-tetrahydro-2H-cyclopenta[b]furan-2-one; (Z)-3-(Hydroxymethylene)hexahydro-2H-cyclopenta[b]furan-2-one; Cyclopentafuranone hydroxymethylene derivative; CAS 194468-85-4; Tetrahydrocyclopentafuranone intermediate; Chiral cyclopenta[b]furan-2-one building block.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-value intermediate. Production adheres to cGMP guidelines where applicable, ensuring batch-to-batch consistency and traceability. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; therefore, containers should be kept sealed under an inert atmosphere after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.