Description

2-Butenoicacid, 4-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Methyl Ester, (2E)- is a specialized chemical intermediate featuring a phthalimide-protected amine group conjugated with an α,β-unsaturated ester moiety. This unique molecular architecture makes it a valuable building block for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials. The compound's defined stereochemistry and functional group compatibility offer precise control in multi-step synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products, leveraging its reactive ester and protected amine functionalities.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal or mechanical properties.
• Material Science: Employed in the research of advanced organic materials, including liquid crystals or organic semiconductors.
• Chemical Synthesis: Utilized as a versatile building block in academic and industrial organic chemistry for constructing complex heterocycles and natural product analogs.
• Bioconjugation: Potential use in developing linker molecules for antibody-drug conjugates (ADCs) or other bioconjugation strategies due to its reactive sites.

Basic Information

Item	Details
Product Name	2-Butenoicacid, 4-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Methyl Ester, (2E)-
CAS No.	194093-31-7
Molecular Formula	C13H11NO4
Molecular Weight	245.23 g/mol
Synonyms	(2E)-4-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-butenoic acid methyl ester; Methyl (2E)-4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)but-2-enoate; 2-Butenoic acid, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, methyl ester, (2E)-; N-Phthalimidoacrylic acid methyl ester; Methyl (E)-4-phthalimidobut-2-enoate; 4-Phthalimidocrotonic acid methyl ester; (E)-Methyl 4-(1,3-dioxoisoindolin-2-yl)but-2-enoate
EINECS	Contact for details

Quality Control

Our production of 2-Butenoicacid, 4-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Methyl Ester, (2E)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing specific batch results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.