Description

1-Piperidineacetic Acid, 4-Carboxy-, 1-(1,1-Dimethylethyl) Ester is a high-purity, functionalized piperidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with high stereochemical control. Pharmaceutical and agrochemical R&D teams need it for developing new active ingredients, particularly in the synthesis of novel APIs and fine chemicals where precise structural modification is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific stereochemistry for optimal efficacy.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry to design and synthesize peptide analogs and conformationally restricted scaffolds.
• Fine Chemical Production: Acts as a specialized intermediate in custom synthesis projects for high-value, low-volume fine chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization studies.

Basic Information

Product Name	1-Piperidineacetic Acid, 4-Carboxy-, 1-(1,1-Dimethylethyl) Ester
CAS No.	193903-41-2
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	tert-Butyl 4-carboxypiperidine-1-acetate; 1-(tert-Butoxycarbonylmethyl)-4-carboxypiperidine; 4-Carboxy-1-piperidineacetic Acid tert-Butyl Ester; 1-Piperidineacetic Acid, 4-Carboxy-, 1,1-Dimethylethyl Ester; 1-Boc-methyl-4-carboxypiperidine; 4-Carboxypiperidine-1-acetic Acid tert-Butyl Ester; N-Boc-N-(carboxymethyl)-4-piperidinecarboxylic Acid; (4-Carboxypiperidin-1-yl)acetic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 1-Piperidineacetic Acid, 4-Carboxy-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.