Description

4,7-Diazaspiro[2.5]Octane-5,8-Dione,6-(1-Methylethyl)-,(S)-(9Ci) is a high-value, chiral spirocyclic compound characterized by its unique diazaspiro[2.5]octane core structure. This compound serves as a sophisticated pharmaceutical intermediate and key building block in the synthesis of complex active molecules, particularly for drug discovery programs targeting central nervous system (CNS) and metabolic diseases. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, stereochemically defined intermediates to accelerate their synthetic routes.

Application

This specialized intermediate is designed for advanced synthetic applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in medicinal chemistry.
• Protease Inhibitor Research: Used in the development of inhibitors for various protease enzymes due to its constrained spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research and development of new, high-performance active ingredients with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Institutional Research: A valuable compound for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4,7-Diazaspiro[2.5]Octane-5,8-Dione,6-(1-Methylethyl)-,(S)-(9Ci)
CAS No.	193740-34-0
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(S)-6-Isopropyl-4,7-diazaspiro[2.5]octane-5,8-dione; (S)-6-(Propan-2-yl)-4,7-diazaspiro[2.5]octane-5,8-dione; (S)-6-Isopropyl-1,4-diazaspiro[2.5]octane-2,3-dione; 4,7-Diazaspiro[2.5]octane-5,8-dione, 6-(1-methylethyl)-, (S)-; (S)-6-(1-Methylethyl)-4,7-diazaspiro[2.5]octane-5,8-dione; (S)-6-Isopropyl-1,4-diazaspiro[2.5]octane-2,3-dione; 193740-34-0; (S)-enantiomer of 6-isopropyl-4,7-diazaspiro[2.5]octane-5,8-dione
EINECS	Contact for details

Quality Control

Our production of 4,7-Diazaspiro[2.5]Octane-5,8-Dione,6-(1-Methylethyl)-,(S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. All materials undergo rigorous analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.