Description

Ethyl Azepane-3-Carboxylate is a versatile heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its azepane (seven-membered nitrogen-containing ring) structure provides a valuable scaffold for constructing complex molecules with specific three-dimensional properties. This compound is particularly valuable for research and development chemists in the pharmaceutical and agrochemical sectors. It serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring a constrained, nitrogen-rich framework.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the azepane ring can contribute to biological activity.
• Catalyst and Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis to produce enantiomerically pure compounds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex heterocyclic libraries.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances that require specific, constrained molecular architectures.

Basic Information

Item	Detail
Product Name	Ethyl Azepane-3-Carboxylate
CAS No.	193560-73-5
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	Ethyl 3-Azepanecarboxylate; 3-(Ethoxycarbonyl)azepane; Azepane-3-carboxylic Acid Ethyl Ester; Ethyl Hexahydroazepine-3-carboxylate; 1-Azacycloheptane-3-carboxylic Acid, Ethyl Ester; NSC 339243; 3-Carbethoxyazepane
EINECS	Contact for details

Quality Control

Our Ethyl Azepane-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, chiral purity (enantiomeric excess), and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting all critical quality attributes. Our quality protocols are designed to meet the stringent requirements of GMP for pharmaceutical intermediates and research-grade chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e. (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.