Description

1-tert-Butyl 3-Methyl 3-Methyl-4-Oxopiperidine-1,3-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidinone-dicarboxylate structure. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily needed by pharmaceutical R&D laboratories, process development chemists, and large-scale API manufacturers seeking reliable, high-quality intermediates for streamlined synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• API Synthesis: Serves as a key building block for constructing the core piperidine scaffold found in various therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable manufacturing routes for target compounds.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical production.

Basic Information

Product Name	1-tert-Butyl 3-Methyl 3-Methyl-4-Oxopiperidine-1,3-Dicarboxylate
CAS No.	193274-53-2
Molecular Formula	C13H21NO5
Molecular Weight	271.31 g/mol
Synonyms	1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate; 3-Methyl-4-oxopiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester; 4-Oxo-3-piperidinecarboxylic acid, 1-(1,1-dimethylethyl) 3-methyl ester; tert-Butyl methyl 3-methyl-4-oxopiperidine-1,3-dicarboxylate; Methyl 1-(tert-butoxycarbonyl)-3-methyl-4-oxopiperidine-3-carboxylate; 1-Boc-3-methyl-4-oxopiperidine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Methyl 3-Methyl-4-Oxopiperidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.