Description

Carbamic Acid, [4-[2-[[(4-Methylphenyl)Sulfonyl]Oxy]Ethyl]Phenyl]-, 1,1-Dimethylethyl Ester is a specialized organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific functional groups or create novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected amine or carbamate functionality.
• Agrochemical Synthesis: Used in research and production pathways for developing new herbicides, fungicides, or insecticides with enhanced efficacy.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules, leveraging its reactive sulfonyloxy and ester groups.
• Peptide Mimetics & PROTACs: Finds application in the design and synthesis of peptide analogs and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymers with specific thermal or chemical properties.
• Bioconjugation Chemistry: Potentially used in linker chemistry for attaching payloads to antibodies or other biological molecules in ADC (Antibody-Drug Conjugate) development.

Basic Information

Product Name	Carbamic Acid, [4-[2-[[(4-Methylphenyl)Sulfonyl]Oxy]Ethyl]Phenyl]-, 1,1-Dimethylethyl Ester
CAS No.	193204-58-9
Molecular Formula	C20H25NO5S
Molecular Weight	391.48 g/mol
Synonyms	tert-Butyl N-[4-[2-[(4-methylphenyl)sulfonyloxy]ethyl]phenyl]carbamate; 1,1-Dimethylethyl [4-[2-[[(4-Methylphenyl)Sulfonyl]Oxy]Ethyl]Phenyl]Carbamate; BOC-Protected Aminosulfonate Ester; 4-[2-(p-Toluenesulfonyloxy)ethyl]phenylcarbamic acid tert-butyl ester; tert-Butyl (4-(2-((p-tolylsulfonyl)oxy)ethyl)phenyl)carbamate; N-Boc-4-(2-tosyloxyethyl)aniline; (4-(2-((4-Methylphenyl)sulfonyloxy)ethyl)phenyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [4-[2-[[(4-Methylphenyl)Sulfonyl]Oxy]Ethyl]Phenyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.