Description

(S)-2-Carboxymethoxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its primary value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other drug discovery programs.
• Peptidomimetic Synthesis: Used in the construction of peptidomimetics and constrained amino acid analogs for drug design.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel, enantiomerically pure agrochemicals with specific biological activity.
• Academic & R&D: A valuable reagent for university and corporate research laboratories exploring new synthetic methodologies and bioactive compounds.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Product Name	(S)-2-Carboxymethoxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	193086-18-9
Molecular Formula	C12H21NO5
Molecular Weight	259.30 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-2-(carboxymethoxymethyl)pyrrolidine; (S)-2-(Carboxymethoxymethyl)-1-Boc-pyrrolidine; (S)-1-Boc-2-(carboxymethoxymethyl)pyrrolidine; (S)-N-Boc-2-(carboxymethoxymethyl)pyrrolidine; (S)-2-(Methoxycarbonylmethyl)-1-Boc-pyrrolidine (related ester); tert-Butyl (S)-2-(carboxymethoxymethyl)pyrrolidine-1-carboxylate; Boc-(S)-CmmP-OH
EINECS	Contact for details

Quality Control

Our (S)-2-Carboxymethoxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.