Description

6-Chloro-4-Methoxy-Pyridine-2-Carbonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic systems.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Chloro-4-Methoxy-Pyridine-2-Carbonitrile
CAS No.	193074-46-3
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	2-Cyano-6-chloro-4-methoxypyridine; 4-Methoxy-6-chloropyridine-2-carbonitrile; 6-Chloro-4-methoxy-2-pyridinecarbonitrile; 6-Chloro-4-methoxypicolinonitrile; 2-Pyridinecarbonitrile, 6-chloro-4-methoxy-; 193074-46-3; 6-Chloro-4-methoxypyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-4-Methoxy-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.