Description

7-Benzyl-5,6,7,8-Tetrahydro4-Chloro-Pyrido[3,4-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the pyridopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific enzymatic pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial precursor in multi-step synthetic routes for the manufacture of final drug substances.
• Biochemical Research: Employed as a reference standard or tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	7-Benzyl-5,6,7,8-Tetrahydro4-Chloro-Pyrido[3,4-D]Pyrimidine Hydrochloride
CAS No.	192869-80-0
Molecular Formula	C₁₆H₁₇ClN₄·HCl
Molecular Weight	337.25 g/mol
Synonyms	7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 4-Chloro-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 192869-80-0; Pyrido[3,4-d]pyrimidine, 7-benzyl-4-chloro-5,6,7,8-tetrahydro-, hydrochloride; 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl
EINECS	Contact for details

Quality Control

Our 7-Benzyl-5,6,7,8-Tetrahydro4-Chloro-Pyrido[3,4-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.