Description

2(3H)-Furanone,5-(2,3-Dihydroxyphenyl)Dihydro-4-Methyl-,(4R,5S)-Rel-(-)-(9Ci) is a high-purity, stereochemically defined chiral compound of significant interest in advanced organic synthesis. Its complex furanone core fused with a dihydroxyphenyl moiety makes it a valuable versatile building block for pharmaceutical research and fine chemical development. This product is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in stereoselective synthesis to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of new-generation, biologically active compounds for crop protection.
• Ligand and Catalyst Development: The dihydroxyphenyl group can be leveraged to develop novel chelating ligands or organocatalysts for metal-mediated or catalytic reactions.
• Material Science Precursor: Potential use in synthesizing specialized monomers or additives for advanced polymeric materials.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	2(3H)-Furanone,5-(2,3-Dihydroxyphenyl)Dihydro-4-Methyl-,(4R,5S)-Rel-(-)-(9Ci)
CAS No.	192707-40-7
Molecular Formula	C11H12O4
Molecular Weight	208.21 g/mol
Synonyms	(4R,5S)-rel-5-(2,3-Dihydroxyphenyl)dihydro-4-methyl-2(3H)-furanone; (-)-5-(2,3-Dihydroxyphenyl)-4-methyl-2(3H)-furanone; 4-Methyl-5-(2,3-dihydroxyphenyl)dihydro-2(3H)-furanone; 192707-40-7; (rel)-(4R,5S)-5-(2,3-Dihydroxyphenyl)-4-methyl-4,5-dihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Every batch of this chiral building block is produced and tested under strict quality management to ensure identity, purity, and stereochemical integrity. We provide comprehensive analytical data including HPLC purity, chiral purity (enantiomeric excess), and spectroscopic confirmation (NMR, IR, MS). A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting all critical quality attributes. Our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.