Description

5-Bromo-1,2,3-triazolo[1,5-a]pyridine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, combining a triazole ring fused to a pyridine, makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This high-purity intermediate is essential for medicinal chemists and R&D scientists developing new active ingredients, where its reactive bromine atom enables efficient cross-coupling and functionalization reactions. The compound is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create biaryl structures.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new chemical space in heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-1,2,3-triazolo[1,5-a]pyridine
CAS No.	192642-77-6
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-[1,2,3]triazolo[1,5-a]pyridine; 5-Bromo-1,2,3-triazolopyridine; 1,2,3-Triazolo[1,5-a]pyridine, 5-bromo-; 192642-77-6; 5-Bromotriazolopyridine; 5-Br-TAP
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3-triazolo[1,5-a]pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.