Description

1-Methyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine is a high-value, nitrogen-containing heterocyclic compound featuring a trifluoromethylpyridine moiety. This structure makes it a critical building block and key intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D and process chemistry teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-donor ligands used in transition metal catalysis for fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme inhibition.

Basic Information

Product Name	1-Methyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine
CAS No.	192564-53-7
Molecular Formula	C11H14F3N3
Molecular Weight	245.25 g/mol
Synonyms	1-Methyl-4-[5-(trifluoromethyl)-2-pyridinyl]piperazine; 2-(4-Methylpiperazin-1-yl)-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-(4-methylpiperazin-1-yl)pyridine; 1-Methyl-4-(5-trifluoromethylpyridin-2-yl)piperazine; N-Methyl-4-(5-trifluoromethyl-2-pyridyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.