Description

Pyridine, 3-Ethynyl-5-((2S)-1-Methyl-2-Pyrrolidinyl)-, (2Z)-2-Butenedioate(1:1) is a high-purity, specialized organic salt compound of significant interest in advanced pharmaceutical research and development. This compound matters as a key chiral intermediate or building block for synthesizing complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly in the areas of neurology and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of novel drug candidates.
• Neurological Research: Used in the development of compounds targeting nicotinic acetylcholine receptors (nAChRs) for potential cognitive or neurological applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Asymmetric Synthesis: Utilized as a source of a chiral pyrrolidine moiety in catalytic or stoichiometric asymmetric transformations.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in API manufacturing.
• Preclinical Development: Used in the synthesis of compounds for in vitro and in vivo pharmacological evaluation.

Basic Information

Item	Detail
Product Name	Pyridine, 3-Ethynyl-5-((2S)-1-Methyl-2-Pyrrolidinyl)-, (2Z)-2-Butenedioate(1:1)
CAS No.	192231-16-6
Molecular Formula	C16H18N2O4
Molecular Weight	302.33 g/mol
Synonyms	(2Z)-2-Butenedioic acid; 3-Ethynyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine (1:1); (Z)-But-2-enedioic acid - 3-ethynyl-5-[(2S)-1-methylpyrrolidin-2-yl]pyridine (1:1); 3-Ethynyl-5-((S)-1-methyl-2-pyrrolidinyl)pyridine maleate; (S)-3-Ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine maleate; Maleic acid salt of 3-Ethynyl-5-((S)-1-methyl-2-pyrrolidinyl)pyridine; 192231-16-6; Research Code Compound (various proprietary names may apply)
EINECS	Contact for details

Quality Control

Our Pyridine, 3-Ethynyl-5-((2S)-1-Methyl-2-Pyrrolidinyl)-, (2Z)-2-Butenedioate(1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the exacting standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.