Description

tert-Butyl 3-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate is a high-purity, protected heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate, enabling the efficient construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its fused heterocyclic core.
• Chemical Biology: Employed in the creation of molecular probes and tool compounds for studying biological processes and target validation.
• Material Science: Serves as a precursor for advanced organic materials, such as organic semiconductors or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploration of new chemical space.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate
CAS No.	192189-17-6
Molecular Formula	C12H13BrN2O2
Molecular Weight	297.15 g/mol
Synonyms	1-Boc-3-bromo-7-azaindole; 3-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester; 3-Bromo-7-azaindole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-bromo-7-azaindole-1-carboxylate; 3-Bromo-1-(tert-butoxycarbonyl)-1H-pyrrolo[2,3-c]pyridine; 1-Boc-3-bromo-1H-pyrrolo[2,3-c]pyridine; Boc-3-bromo-7-azaindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.