Description

tert-Butyl 5-oxopentanoate is a high-purity chemical intermediate featuring a protected carboxylic acid group and a reactive ketone functionality. This compound matters for its versatility in multi-step organic synthesis, particularly in the construction of complex molecules where selective deprotection and further functionalization are required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the production of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a levulinic acid derivative or a γ-keto ester moiety.
• Peptide Synthesis: Serves as a protected form of glutamic acid or as a scaffold for introducing ketone handles into peptide chains for bioconjugation (e.g., oxime ligation).
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Organic Synthesis: Versatile precursor for various transformations, including Grignard additions, reductions, and reductive aminations at the ketone group, followed by tert-butyl ester deprotection.
• Fragrance and Flavor Industry: Intermediate for the synthesis of complex ester and lactone compounds used in specialty fragrances.

Basic Information

Product Name	tert-Butyl 5-Oxopentanoate
CAS No.	192123-41-4
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	5-Oxopentanoic acid tert-butyl ester; tert-Butyl levulinate; Levulinic acid tert-butyl ester; tert-Butyl 4-oxobutanoate; Butanoic acid, 4-oxo-, 1,1-dimethylethyl ester; 192123-41-4; t-Butyl levulinate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-oxopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.