Description

1,4-Dihydro-2-Methyl-6-Phenyl-4-(Phenylethynyl)-3,5-Pyridinedicarboxylic Acid 3-Ethyl-5-[(3-Nitrophenyl)Methyl] Ester is a specialized, high-purity organic compound with the CAS registry number 192053-05-7. This molecule is valued for its complex dihydropyridine core, which serves as a critical pharmacophore and synthetic intermediate in advanced chemical synthesis. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel calcium channel blockers and other therapeutic agents based on the dihydropyridine scaffold.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Fine Chemical Synthesis: Serves as a precursor for creating complex, functionalized organic molecules with specific electronic or steric properties.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1,4-Dihydro-2-Methyl-6-Phenyl-4-(Phenylethynyl)-3,5-Pyridinedicarboxylic Acid 3-Ethyl-5-[(3-Nitrophenyl)Methyl] Ester
CAS No.	192053-05-7
Molecular Formula	C33H28N2O6
Molecular Weight	548.59 g/mol
Synonyms	3-Ethyl 5-[(3-nitrophenyl)methyl] 2-methyl-4-(2-phenylethynyl)-6-phenyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-(Phenylethynyl)-1,4-dihydro-2-methyl-6-phenyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-[(3-nitrophenyl)methyl] ester; DHP derivative CAS 192053-05-7; 1,4-DHP Ester Nitrophenyl Derivative; Ethyl Methyl DHP Ester Nitrobenzyl; Aryl-Substituted Dihydropyridine Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.