Description

(1R,2S)-2-Aminocyclohexanecarboxylic Acid Ethyl Ester is a chiral, non-proteinogenic amino acid derivative of significant synthetic utility. This compound serves as a crucial chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide mimetics, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel chiral herbicides, fungicides, and plant growth regulators.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis to introduce the 1R,2S-aminocyclohexyl moiety.
• Peptidomimetics & Drug Discovery: Integral for constructing conformationally constrained peptide analogs and probing structure-activity relationships in medicinal chemistry.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, catalysts, and ligands used in various chemical processes.

Basic Information

Product Name	(1R,2S)-2-Aminocyclohexanecarboxylic Acid Ethyl Ester
CAS No.	192047-04-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (1R,2S)-2-aminocyclohexanecarboxylate; L-2-Aminocyclohexanecarboxylic Acid Ethyl Ester (1R,2S); (1R,2S)-2-Amino-1-cyclohexanecarboxylic Acid Ethyl Ester; trans-2-Aminocyclohexanecarboxylic Acid Ethyl Ester (1R,2S); Ethyl trans-2-aminocyclohexane-1-carboxylate; ACC Ethyl Ester; 2-Aminocyclohexanecarboxylic Acid, Ethyl Ester, trans- (1R,2S)-
EINECS	Contact for details

Quality Control

Our (1R,2S)-2-Aminocyclohexanecarboxylic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.