Description

tert-Butyl 4-((Methoxycarbonyl)Methyl)Benzylcarbamate is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality intermediates for peptide synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce protected amino acid functionalities.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• Bioconjugation: Can be utilized in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals.
• Custom Synthesis: An important starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	tert-Butyl 4-((Methoxycarbonyl)Methyl)Benzylcarbamate
CAS No.	191871-32-6
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Boc-4-(Methoxycarbonylmethyl)benzylamine; 4-[(tert-Butoxycarbonylamino)methyl]benzeneacetic acid methyl ester; Methyl [4-[[(tert-butoxy)carbonylamino]methyl]phenyl]acetate; tert-Butyl N-[[4-(methoxycarbonylmethyl)phenyl]methyl]carbamate; Boc-Amino-Phe(4-CH2CO2Me)-OH methyl ester; (4-((tert-Butoxycarbonylamino)methyl)phenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((Methoxycarbonyl)Methyl)Benzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.