Description

Methyl 2-Phenylalaninate Hydrochloride is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of 2-phenylalanine. This compound serves as a crucial chiral building block and intermediate in sophisticated organic synthesis, particularly for the preparation of peptides and peptidomimetics. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries who require high-purity, enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected phenylalanine derivative.
• Biochemical Research: Employed in proteomics research and as a standard or reagent in enzymatic and metabolic studies.
• Fine Chemical Production: Acts as a precursor for the manufacture of complex organic molecules, flavors, and fragrances.
• Asymmetric Synthesis: Utilized in catalytic asymmetric reactions to introduce the 2-phenylglycine moiety into target molecules.
• Academic & R&D: Serves as a valuable compound for methodological development in academic and industrial research laboratories.

Basic Information

Product Name	Methyl 2-Phenylalaninate Hydrochloride
CAS No.	191796-90-4
Molecular Formula	C10H13NO2 • HCl
Molecular Weight	215.68 g/mol (Free base: 179.22)
Synonyms	Methyl (R)-2-Phenylglycinate Hydrochloride; (R)-Methyl 2-Amino-2-phenylacetate Hydrochloride; D-2-Phenylglycine Methyl Ester Hydrochloride; Methyl α-Phenylglycinate Hydrochloride; (R)-2-Phenylglycine Methyl Ester HCl; Methyl (R)-α-Aminophenylacetate Hydrochloride; (R)-Methyl 2-Phenyl-2-aminoacetate Hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-Phenylalaninate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.