Description

1,7-Dioxaspiro5.5Undecane, 3-Methoxy-5-(Phenylmethoxy)-, (3.Alpha.,5.Alpha.,6.Beta.)- is a high-purity, specialized spirocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a versatile chiral building block and intermediate for the development of complex pharmacologically active molecules. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic research institutions focused on medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Asymmetric Synthesis: Utilized as a sophisticated scaffold or chiral auxiliary to induce stereoselectivity in complex organic reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Fragrance and Flavor Chemistry: Potential use as an intermediate for creating unique spirocyclic odorants and flavoring substances due to its complex structure.
• Academic Research: Serves as a model compound in studies of spirocyclic chemistry, etherification reactions, and stereochemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1,7-Dioxaspiro5.5Undecane, 3-Methoxy-5-(Phenylmethoxy)-, (3.Alpha.,5.Alpha.,6.Beta.)-
CAS No.	191659-93-5
Molecular Formula	C17H24O4
Molecular Weight	292.37 g/mol
Synonyms	(3α,5α,6β)-3-Methoxy-5-(phenylmethoxy)-1,7-dioxaspiro[5.5]undecane; 3-Methoxy-5-(benzyloxy)-1,7-dioxaspiro[5.5]undecane; 1,7-Dioxaspiro[5.5]undecane, 3-methoxy-5-(phenylmethoxy)-, (3α,5α,6β)-; Spirocyclic benzyl ether; Chiral spiroketal ether.
EINECS	Contact for details

Quality Control

Our high-purity grade of this spirocyclic intermediate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.