Description

Spiro3,7-Dioxabicyclo4.1.0Heptane-4,2-2Hpyran, Tetrahydro-5-Methoxy-, (1.Alpha.,4.Alpha.,5.Beta.,6.Alpha.)- is a specialized spirocyclic ether compound with a unique bicyclic structure, offering significant value as a versatile chiral building block and intermediate in advanced organic synthesis. Its complex, rigid framework makes it particularly valuable for constructing intricate molecular architectures where stereochemical control is paramount. This high-purity intermediate is essential for research and development in the pharmaceutical, agrochemical, and fine chemical sectors, where it is used to develop novel active ingredients and functional materials. CAS No. 191659-80-0.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its spirocyclic structure for enhanced biological activity.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, including flavors, fragrances, and advanced polymer modifiers.
• Asymmetric Catalysis Ligand Precursor: Its defined stereochemistry makes it a valuable starting material for developing novel chiral ligands and organocatalysts.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing oxygen-containing heterocycles and spiro compounds.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.

Basic Information

Product Name	Spiro3,7-Dioxabicyclo4.1.0Heptane-4,2-2Hpyran, Tetrahydro-5-Methoxy-, (1.Alpha.,4.Alpha.,5.Beta.,6.Alpha.)-
CAS No.	191659-80-0
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1α,4α,5β,6α)-Tetrahydro-5-methoxyspiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran]; 5-Methoxyspiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran], tetrahydro-, (1α,4α,5β,6α)-; Spiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran], tetrahydro-5-methoxy-, (1α,4α,5β,6α)-; Tetrahydro-5-methoxyspiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran] (stereoisomer); Chiral Spirocyclic Ether Intermediate; Spirocyclic Ether Synthon.
EINECS	Contact for details

Quality Control

Our Spiro3,7-Dioxabicyclo4.1.0Heptane-4,2-2Hpyran, Tetrahydro-5-Methoxy-, (1.Alpha.,4.Alpha.,5.Beta.,6.Alpha.)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.