Description

Spiro3,7-Dioxabicyclo4.1.0Heptane-4,2-2Hpyran-5-Ol, Tetrahydro-, (1.Alpha.,4.Alpha.,5.Beta.,6.Alpha.)- is a complex spirocyclic ether-alcohol compound with a unique bicyclic structure. This specialized chemical serves as a valuable high-purity intermediate or building block for advanced organic synthesis, enabling the construction of novel molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing new active ingredients, agrochemicals, or functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) or anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced pesticides or herbicides where its spirocyclic core contributes to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance molecules, flavors, or other high-value specialty chemicals.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new ring-forming reactions and stereoselective transformations.

Basic Information

Item	Detail
Product Name	Spiro3,7-Dioxabicyclo4.1.0Heptane-4,2-2Hpyran-5-Ol, Tetrahydro-, (1.Alpha.,4.Alpha.,5.Beta.,6.Alpha.)-
CAS No.	191659-67-3
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1α,4α,5β,6α)-Tetrahydrospiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran]-5-ol; Tetrahydrospiro(3,7-dioxabicyclo(4.1.0)heptane-4,2'-(2'H)pyran)-5-ol, (1α,4α,5β,6α)-; Spiro[3,7-dioxabicyclo[4.1.0]heptane-4,2'-[2H]pyran]-5-ol, tetrahydro-, (1α,4α,5β,6α)-; CAS 191659-67-3; Spirocyclic ether-alcohol; Bicyclic spiro ether alcohol intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with full chromatographic data are provided, and we support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the grade. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.