Description

Spiro3,7-Dioxabicyclo4.1.0Heptane-2,2-2Hpyran, Tetrahydro-, (1.Alpha.,2.Alpha.,6.Alpha.)- is a specialized spirocyclic ether compound of significant interest in advanced organic synthesis. Its unique, rigid bicyclic structure makes it a valuable chiral building block and intermediate for the development of complex molecules. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and fine chemical industries. It enables the synthesis of novel active ingredients and functional materials where precise stereochemistry and molecular architecture are critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules for medicinal chemistry.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and high-value performance materials.
• Academic and Industrial Research: Used in methodological studies and process chemistry development within R&D laboratories.
• Material Science: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Spiro3,7-Dioxabicyclo4.1.0Heptane-2,2-2Hpyran, Tetrahydro-, (1.Alpha.,2.Alpha.,6.Alpha.)-
CAS No.	191659-50-4
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(1α,2α,6α)-Tetrahydrospiro[3,7-dioxabicyclo[4.1.0]heptane-2,2'-pyran]; Spiro[3,7-dioxabicyclo[4.1.0]heptane-2,2'-pyran], tetrahydro-, (1α,2α,6α)-; Tetrahydrospiro[3,7-dioxabicyclo[4.1.0]heptane-2,2'-pyran]; Spirocyclic ether intermediate 191659-50-4; Chiral spiroether; Oxaspiro compound CAS 191659-50-4
EINECS	Contact for details

Quality Control

Our production of Spiro3,7-Dioxabicyclo4.1.0Heptane-2,2-2Hpyran, Tetrahydro-, (1.Alpha.,2.Alpha.,6.Alpha.)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, impurity profile, and specific rotation to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.