Description

4-Pentynoicacid,2-Amino-3,3-Dimethyl-,Methylester(9Ci) is a specialized alkyne-containing amino acid derivative, identified by CAS NO 191615-42-6. This compound is a valuable synthetic intermediate prized for its unique molecular scaffold, which combines a reactive terminal alkyne group with a protected amino acid ester functionality. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide mimetics, and the synthesis of complex bioactive molecules.

Application

This advanced chemical intermediate enables key synthetic transformations in research and development. Its primary applications include:

• Pharmaceutical Research: Serving as a crucial building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and for creating peptide mimetics and constrained analogs.
• Click Chemistry: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Agrochemical Development: Acting as a key intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Utilized in the development of chemical probes and bioconjugation strategies for studying biological systems.
• Material Science: Potential use in the synthesis of specialized polymers and functionalized surfaces.

Basic Information

Product Name	4-Pentynoicacid,2-Amino-3,3-Dimethyl-,Methylester(9Ci)
CAS No.	191615-42-6
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	Methyl 2-amino-3,3-dimethyl-4-pentynoate; 2-Amino-3,3-dimethyl-4-pentynoic acid methyl ester; 4-Pentynoic acid, 2-amino-3,3-dimethyl-, methyl ester; 2-Amino-3,3-dimethylpent-4-ynoic acid methyl ester; 191615-42-6; Methyl (2-amino-3,3-dimethylpent-4-ynoate)
EINECS	Contact for details

Quality Control

Our production of 4-Pentynoicacid,2-Amino-3,3-Dimethyl-,Methylester(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results from HPLC, NMR, and other relevant tests are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.