Description

2-Hydroxy-6-(Trifluoromethyl)Nicotinicacid is a high-value trifluoromethyl-substituted pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a carboxylic acid group with a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials and liquid crystals.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes.

Basic Information

Product Name	2-Hydroxy-6-(Trifluoromethyl)Nicotinicacid
CAS No.	191595-63-8
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	6-(Trifluoromethyl)-2-hydroxynicotinic acid; 2-Hydroxy-6-(trifluoromethyl)pyridine-3-carboxylic acid; 2-Hydroxy-6-trifluoromethylnicotinic acid; 3-Carboxy-6-(trifluoromethyl)-2-pyridinol; 2-Pyridinol, 6-(trifluoromethyl)-3-carboxy-; 191595-63-8; Nicotinic acid, 2-hydroxy-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-(Trifluoromethyl)Nicotinicacid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.