Description

2,6-Bis(tert-Butyl)Pyridine-4-Carboxylic Acid is a sterically hindered pyridine derivative that serves as a versatile and highly functionalized organic building block. Its value lies in the unique combination of a carboxylic acid group for derivatization and bulky tert-butyl groups that provide significant steric protection and influence electronic properties. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require sophisticated intermediates for catalyst ligands, active pharmaceutical ingredients (APIs), and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly as a building block for complex heterocyclic systems.
• Catalyst Ligand Synthesis: Used to create sterically demanding ligands for transition metal catalysts in asymmetric synthesis and polymerization processes.
• Advanced Material Development: Serves as a monomer or functional additive in the production of high-performance polymers and organic electronic materials.
• Agrochemical Research: Employed in the development of new crop protection agents and plant growth regulators.
• Coordination Chemistry: Acts as a chelating agent or auxiliary ligand in the formation of metal-organic frameworks (MOFs) and complexes.
• Chemical Synthesis Reagent: Utilized in organic synthesis as a protected or functionalized pyridine scaffold for further chemical transformations.

Basic Information

Item	Details
Product Name	2,6-Bis(tert-Butyl)Pyridine-4-Carboxylic Acid
CAS No.	191478-92-9
Molecular Formula	C₁₅H₂₁NO₂
Molecular Weight	247.33 g/mol
Synonyms	2,6-Di-tert-butylisonicotinic acid; 2,6-Di-tert-butyl-4-pyridinecarboxylic acid; 4-Carboxy-2,6-di-tert-butylpyridine; 2,6-Bis(1,1-dimethylethyl)-4-pyridinecarboxylic acid; DTBP; 2,6-DTBP-4-COOH; Isonicotinic acid, 2,6-bis(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our production of 2,6-Bis(tert-Butyl)Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.