Description

2-Amino-6-(trifluoromethyl)nicotinamide is a high-value, multi-functional chemical intermediate characterized by its pyridine core and trifluoromethyl substituent. This compound matters for its role in facilitating complex molecular synthesis, particularly in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine-containing motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a precursor for functionalized ligands and organic frameworks used in catalysis and material design.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Fluorine Chemistry: A valuable reagent for introducing fluorine-containing groups into complex organic molecules, leveraging its reactive amino and amide functionalities.

Basic Information

Product Name	2-Amino-6-(trifluoromethyl)nicotinamide
CAS No.	191478-53-2
Molecular Formula	C7H6F3N3O
Molecular Weight	205.14 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)pyridine-3-carboxamide; 3-Pyridinecarboxamide, 2-amino-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-aminonicotinamide; 2-Amino-6-trifluoromethylnicotinamide; 2-Amino-6-(trifluoromethyl)-3-pyridinecarboxamide; 2-Amino-6-(trifluoromethyl)nicotinic acid amide; 191478-53-2
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(trifluoromethyl)nicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.