Description

1,3-Dioxolane-4-Acetic Acid, 2-Phenyl-, Methyl Ester, (S) is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized dioxolane ring system make it a critical precursor for the development of complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking to construct sophisticated molecular architectures with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and fragrances requiring specific stereochemistry.
• Academic and R&D: Used in university and industrial research laboratories for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	1,3-Dioxolane-4-Acetic Acid, 2-Phenyl-, Methyl Ester, (S)
CAS No.	191354-59-3
Molecular Formula	C12H14O5
Molecular Weight	238.24 g/mol
Synonyms	(S)-Methyl 2-phenyl-1,3-dioxolane-4-acetate; (4S)-2-Phenyl-1,3-dioxolane-4-acetic acid methyl ester; Methyl (S)-2-phenyl-1,3-dioxolane-4-acetate; (S)-2-Phenyl-1,3-dioxolane-4-acetic acid methyl ester; (S)-4-(Methoxycarbonylmethyl)-2-phenyl-1,3-dioxolane; (S)-Methyl (2-phenyl-1,3-dioxolan-4-yl)acetate
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Acetic Acid, 2-Phenyl-, Methyl Ester, (S) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.