Description

(R)-Methyl Tetrahydrofuran-3-Carboxylate CAS NO 191347-93-0 is a high-value chiral building block and intermediate in organic synthesis. Its significance lies in its stereochemically defined tetrahydrofuran ring, which is a privileged scaffold found in numerous biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing new active pharmaceutical ingredients (APIs) and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of antiviral, anticancer, and central nervous system (CNS) active drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or starting material in stereoselective reactions to construct complex molecular architectures.
• Natural Product Synthesis: Building block for the total synthesis of natural products containing tetrahydrofuran or butyrolactone motifs.
• Agrochemical Research: Intermediate in the development of novel, stereospecific herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in transition metal catalysis.
• Flavor and Fragrance Industry: Potential intermediate for creating stereochemically pure aroma chemicals.

Basic Information

Product Name	(R)-Methyl Tetrahydrofuran-3-Carboxylate
CAS No.	191347-93-0
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(R)-3-(Methoxycarbonyl)tetrahydrofuran; Methyl (R)-Tetrahydrofuran-3-carboxylate; (R)-Tetrahydrofuran-3-carboxylic Acid Methyl Ester; (3R)-Tetrahydro-3-furancarboxylic Acid Methyl Ester; (R)-Methyl 3-Tetrahydrofurancarboxylate; (R)-Methyl 3-THF-carboxylate; (R)-MTHFC
EINECS	Contact for details

Quality Control

Our (R)-Methyl Tetrahydrofuran-3-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.