Description

Methyl 2-Bromo-3,3-Dimethoxypropanoate is a versatile brominated ester building block with a protected carbonyl group, making it a valuable intermediate in synthetic organic chemistry. Its unique structure allows for selective transformations, enabling the synthesis of complex molecules with high precision and efficiency. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules, particularly those requiring chiral centers or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromine atom and masked aldehyde functionality enable specific modes of action.
• Organic Synthesis Building Block: Serves as a precursor for various functional groups, including aldehydes, acids, and other esters, via controlled deprotection and substitution reactions.
• Material Science Research: Employed in the development of novel polymers and specialty chemicals that require specific bromo-ester functionalities.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	Methyl 2-Bromo-3,3-Dimethoxypropanoate
CAS No.	191330-98-0
Molecular Formula	C6H11BrO4
Molecular Weight	227.06 g/mol
Synonyms	2-Bromo-3,3-dimethoxypropanoic acid methyl ester; Methyl 2-bromo-3,3-dimethoxypropionate; Propanoic acid, 2-bromo-3,3-dimethoxy-, methyl ester; Methyl α-bromo-β,β-dimethoxypropionate; 191330-98-0; Methyl 2-bromo-3,3-dimethoxypropanoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-3,3-Dimethoxypropanoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density	~1.4 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.