Description

4,5,6,7-Tetrahydro-1H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid Hydrochloride is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its core imidazopyridine scaffold is a privileged structure in medicinal chemistry, making this compound a critical starting material for the development of novel active pharmaceutical ingredients (APIs). This material is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking to synthesize complex molecules with potential therapeutic applications.

Application

This advanced intermediate is primarily utilized in sophisticated synthetic pathways. Its applications include:

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities based on the imidazopyridine core.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential APIs under Good Manufacturing Practice (GMP) guidelines.
• Chemical Biology Probes: Acts as a precursor for creating specialized molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services to the life sciences sector.

Basic Information

Item	Details
Product Name	4,5,6,7-Tetrahydro-1H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid Hydrochloride
CAS No.	191327-29-4
Molecular Formula	C7H10ClN3O2
Molecular Weight	203.63 g/mol
Synonyms	6-Carboxy-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine hydrochloride; 1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 4,5,6,7-tetrahydro-, hydrochloride; 4,5,6,7-Tetrahydroimidazo[4,5-c]pyridine-6-carboxylic acid HCl; Imidazo[4,5-c]pyridine-6-carboxylic acid, 4,5,6,7-tetrahydro-, hydrochloride (1:1); 191327-29-4 (CAS)
EINECS	Contact for details

Quality Control

Our production of 4,5,6,7-Tetrahydro-1H-Imidazo[4,5-C]Pyridine-6-Carboxylic Acid Hydrochloride adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.