Description

Lasofoxifene Hcl is a selective estrogen receptor modulator (SERM) pharmaceutical intermediate. This compound is critical for the development and production of targeted therapies for postmenopausal osteoporosis and breast cancer. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in hormone-related therapeutic development. Our supply ensures high purity and batch-to-batch consistency for reliable formulation and research outcomes.

Application

• Pharmaceutical Active Ingredient (API) for the synthesis of final drug products targeting estrogen receptor-positive conditions.
• Research & Development of novel Selective Estrogen Receptor Modulators (SERMs) and related endocrine therapies.
• Reference Standard for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Preclinical Studies for evaluating efficacy and safety profiles in models of osteoporosis and breast cancer.
• Process Chemistry for scaling up synthesis and optimizing manufacturing routes for commercial production.

Basic Information

Product Name	Lasofoxifene Hcl
CAS No.	190791-29-8
Molecular Formula	C28H27F2NO3 • HCl
Molecular Weight	500.0 g/mol (approx.)
Synonyms	Lasofoxifene Hydrochloride; (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol hydrochloride; CP-336,156; Fablyn (brand name); Fablyn Hydrochloride; Lasofoxifene HCl; Lasofoxifene Hydrochloride (CP-336,156)
EINECS	Contact for details

Quality Control

Our Lasofoxifene Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.